• Title of article

    Straightforward Bienaymé and copper catalyzed N-arylation sequence to access diverse 5H-pyrido[2′,1′:2,3]imidazo[4,5-b]indoles and analogues

  • Author/Authors

    Ahmed El Akkaoui، نويسنده , , Marie-Aude Hiebel، نويسنده , , Abderrahim Mouaddib، نويسنده , , Sabine Berteina-Raboin، نويسنده , , Gérald Guillaumet، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    8
  • From page
    9131
  • To page
    9138
  • Abstract
    A two-step sequence is reported giving access to diverse 5H-pyrido[2′,1′:2,3]imidazo[4,5-b]indoles and analogues via a Bienaymé multicomponent reaction followed by N-arylation. The desired polycylic scaffolds were obtained in high yield using copper iodide in association with TMEDA in aqueous or dioxane media.
  • Keywords
    isocyanide , Heterocycle , multicomponent reaction , Bienaymé reaction , N-arylation
  • Journal title
    Tetrahedron
  • Serial Year
    2012
  • Journal title
    Tetrahedron
  • Record number

    1105090