Title of article
Chemo-enzymatic preparation of α-6-sulfoquinovosyl-1,2-O-diacylglycerols
Author/Authors
Emiliano Manzo، نويسنده , , Annabella Tramice، نويسنده , , Dario Pagano، نويسنده , , Antonio Trincone، نويسنده , , Angelo Fontana، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
7
From page
10169
To page
10175
Abstract
Synthesis of α-6-sulfoquinovosyl-1,2-O-diacylglycerols is achieved by a versatile chemo-enzymatic stereoselective procedure that involves the use of α-d-glucosidase activity from the Mediterranean mollusc Aplysia fasciata. The synthetic procedure is designed to obtain a wide diversity of regio- and stereo-isomers of these compounds that have gained great interest as antineoplastic agents and potent inhibitors of DNA polymerases.
Keywords
Sulfo-glycolipid , Sulfoquinovosyl-monoacylglycerol , ?-d-Glucosidase , Sulfoquinovosyl-diacylglycerol , Chemo-enzymatic synthesis
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1105197
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