Title of article
Stereoselective cyanation of 4-formyl and 4-imino-β-lactams: application to the synthesis of polyfunctionalized γ-lactams
Author/Authors
Benito Alcaide، نويسنده , , Pedro Almendros، نويسنده , , Gema Cabrero، نويسنده , , M. Pilar Ruiz، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
8
From page
10761
To page
10768
Abstract
The stereoselective reaction of 4-oxoazetidine-2-carbaldehydes and their corresponding imines with cyanide-based reagents give β-lactam α-aminonitriles, which are chameleonic building blocks for the controlled synthesis of a variety of new compounds including functionalized γ-lactams, succinimide derivatives, and diamino-lactams derivatives in optically pure form.
Keywords
Cyanides , Imines , ?-Lactams , rearrangements , ?-Lactams
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1105263
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