Title of article
Metal-free dual sp3 C–H functionalization: I2-promoted domino oxidative cyclization to construct 2,5-disubstituted oxazoles
Author/Authors
Qing-He Gao، نويسنده , , Zhuan Fei، نويسنده , , Yan-Ping Zhu، نويسنده , , Mi Lian، نويسنده , , Feng-Cheng Jia، نويسنده , , Mei-Cai Liu، نويسنده , , Neng-Fang She، نويسنده , , An-Xin Wu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
7
From page
22
To page
28
Abstract
An I2-promoted sp3 C–H functionalization has been developed for the synthesis of 2,5-disubstituted oxazoles from easily available methyl ketones and benzylamines without any metal and peroxide catalyst. This domino oxidative cyclization process involves the cleavage of C–H bond and the formation of C–N, C–O bonds.
Keywords
I2-promoted , sp3 C–H functionalization , Domino oxidative cyclization , oxazoles
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105272
Link To Document