Author/Authors :
Lyudmila F. Lourie، نويسنده , , Yurii A. Serguchev، نويسنده , , Maxim V. Ponomarenko، نويسنده , , Eduard B. Rusanov، نويسنده , , Michail V. Vovk، نويسنده , , Nikolai V. Ignatʹev، نويسنده ,
Abstract :
Fluorocyclization of phenyl-substituted alkenols in ionic liquids under action of N–F reagents namely F-TEDA-BF4 and N-fluorobenzenesulfonimide has been studied. Opposite to the non-stereoselective reaction in organic solvents the reaction in ionic liquids resulted in the formation preferably of the trans-diastereomeric fluorinated cyclic ethers. 2-Difluoromethyl-2-phenyl-tetrahydrofuran was obtained by interaction of 4-phenylpent-4-en-1-ol with F-TEDA-BF4 in ionic liquids.
