Cooperatively assisted N-arylation using organic ionic base–Brønsted acid combination under controlled microwave heating

A new synthetic strategy is developed for the construction of C–N bond through the assistance of Brønsted acid/[DBU][HOAc] without adding any metal catalyst. This is the first efficient SNAr methodology utilizing fluoro, chloro, bromo, and iodoarenes as coupling partners, which offers excellent yield up to 94% within a very short time.