Title of article :
The PdCl2-catalyzed sequential heterocyclization/Michael addition cascade in the synthesis of 2,3-disubstituted indoles
Author/Authors :
Donala Janreddy، نويسنده , , Veerababurao Kavala، نويسنده , , Chunwei Kuo، نويسنده , , Ting-Shen Kuo، نويسنده , , Chiu-Hui He، نويسنده , , Ching-Fa Yao، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A cascade reaction of 2-N-unprotected-2-alkynylanilines and various electron-deficient alkenes in the presence of PdCl2 provided 2,3-disubstituted indole derivatives, whereas, in the presence of Pd(OAc)2, the same reaction resulted in the production of N-alkylated-2-alkynylaniline derivatives.
Keywords :
? , ?-Unsaturated ketones , cascade reaction , PdCl2 , 2 , 2-Alkynylanilines , 3-Disubstituted indoles
Journal title :
Tetrahedron
Journal title :
Tetrahedron
