Title of article :
A method for the regioselective synthesis of 1-alkyl-1H-indazoles
Author/Authors :
Hanjun Liu، نويسنده , , Shiang-Fu Hung، نويسنده , , Chuan-Lin Chen، نويسنده , , Mei-Huey Lin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A method for the regioselective synthesis of 3-unsubstituted 1-alkyl-1H-indazoles, starting with 2-halobenzonitriles and N-alkylhydrazines, is described. The two-step reaction pathway proceeds through the intermediacy of 1-alkyl-3-amino-1H-indazoles followed by reductive deamination.
Keywords :
indazoles , 2-Halobenzonitriles , N-Alkylhydrazines , Deamination , Regioselective
Journal title :
Tetrahedron
Journal title :
Tetrahedron