Title of article
Convenient synthesis of perfluoroalkyl substituted 2-oxopyridine-fused 1,3-diazaheterocycles via a one-pot three-component reaction
Author/Authors
Zewei Wang، نويسنده , , Tianqi Sun، نويسنده , , Jie Chen، نويسنده , , Hongmei Deng، نويسنده , , Min Shao، نويسنده , , Hui Zhang، نويسنده , , Weiguo Cao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
6
From page
4270
To page
4275
Abstract
An efficient one-pot synthesis of perfluoroalkylated ring-fused 2-pyridones by three-component reaction of diamine, ketene dithioacetal, and methyl 2-perfluoroalkynoate in EtOH is reported. This protocol has the advantages of easiness, higher yields, and shorter reaction time. A plausible mechanism for this type of cyclization is proposed.
Keywords
Ketene dithioacetal , Perfluoroalkylated ring-fused 2-pyridone , One-pot synthesis , Methyl 2-perfluoroalkynoate , multicomponent reaction
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105785
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