Title of article
Synthesis of phosphinodepsipeptides via the pseudo-four-component condensation reaction
Author/Authors
Fanhua Meng، نويسنده , , Jiaxi Xu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
9
From page
4944
To page
4952
Abstract
Phosphinodepsipeptides are recognized as an important class of enzyme inhibitors as tetrahedrally structural transition-state analogues to natural peptides. A series of phosphinodepsipeptides was synthesized in satisfactory yields via pseudo-four-component condensation reaction of 2-(N-benzoxycarbonylamino)alkanamides/peptide amides, aldehydes, and aryldichlorophosphines, followed by alcoholysis with hydroxyl esters.
Keywords
Alcoholysis , Four-component condensation , Peptide , Phosphinodepsipeptide , Amino amide
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105861
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