Title of article
A Simple Stereoselective Access to (alpha)-Trifluoromethylated Piperidines
Author/Authors
Bariau، Annabelle نويسنده , , Roblin، Jean-Philippe نويسنده , , Troin، Yves نويسنده , , Canet، Jean-Louis نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-1730
From page
1731
To page
0
Abstract
An intramolecular Mannich-type reaction, involving either an (alpha)-trifluoromethyl-1,3-aminoketal or a fluoral synthetic equivalent, was employed to prepare diastereoselectively (alpha)-trifluoromethylpiperidines. This simple strategy allows a facile access to a wide range of new (alpha)-trifluoromethyl saturated N-heterocyclic compounds.
Keywords
piperidines , Fluorine , intramolecular Mannich reaction , diastereoselectivity
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110594
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