Title of article
Synthesis of 5-amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonic acid derivatives and their use in the preparation of phosphorylated peptidomimetics
Author/Authors
Kostyantyn M. Kondratyuk، نويسنده , , Olena I. Lukashuk، نويسنده , , Aleksandr V. Golovchenko، نويسنده , , Igor V. Komarov، نويسنده , , Volodymyr S. Brovarets، نويسنده , , Valery P. Kukhar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
11
From page
6251
To page
6261
Abstract
Starting from phthalimidoalkanoylamines 1 (amino-protected derivatives of glycine, β-alanine, γ-amino butyric, δ-amino valeric, and ε-amino caproic acids), a facile synthetic method has been developed to obtain diethyl 5-alkyl(dialkyl)amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonates 7, which have been further used in the preparation of phosphorylated peptidomimetics 10 and 12.
Keywords
oxazole , Aminophosphonic acid , Amino acid , Phosphono peptidomimetic
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106025
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