Title of article
Highly diastereoselective 1,3-dipolar cycloaddition of nonstabilized azomethine ylides to 3-nitro-2-trihalomethyl-2H-chromenes: synthesis of 1-benzopyrano[3,4-c]pyrrolidines
Author/Authors
Vladislav Yu. Korotaev، نويسنده , , Alexey Yu. Barkov، نويسنده , , Vladimir S. Moshkin، نويسنده , , Evgeniya G. Matochkina، نويسنده , , Mikhail I. Kodess، نويسنده , , Vyacheslav Ya Sosnovskikh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
7
From page
8602
To page
8608
Abstract
Reactions of 3-nitro-2-trifluoro(trichloro)methyl-2H-chromenes, including 2-unsubstituted derivatives, with N-alkyl-α-amino acids (sarcosine, proline) and paraformaldehyde proceed diastereoselectively to give 1-benzopyrano[3,4-c]pyrrolidines in good yields as a result of a 1,3-dipolar cycloaddition of the intermediate nonstabilized azomethine ylide at the Δ3-bond of the chromene system.
Keywords
3-Nitro-2H-chromenes , Nonstabilized azomethine ylides , 1 , 4-c]pyrrolidines , 3-dipolar cycloaddition
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106298
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