Title of article :
Iron-Catalyzed Chemoselective Cross-Coupling of Primary and Secondary Alkyl Halides with Arylzinc Reagents
Author/Authors :
Nakamura، Eiichi نويسنده , , Nakamura، Masaharu نويسنده , , Ito، Shingo نويسنده , , Matsuo، Keiko نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Functional-group-compatible cross-coupling reaction of alkyl halides with arylzinc reagents takes place under iron catalysis in the presence of TMEDA, producing a variety of aromatic compounds in good to excellent yield. The pronounced effect of a magnesium salt was found to be the key to the promotion of the iron-catalyzed coupling reaction.
Keywords :
cross-coupling , alkyl halides , substitution , zinc reagents , iron catalyst
