Title of article
Electrochemical synthesis of glycoconjugates of 3β-hydroxy-Δ5-steroids by using non-activated sugars and steroidal thioethers
Author/Authors
Aneta M. Tomkiel، نويسنده , , Krzysztof Brzezinski، نويسنده , , Zenon ?otowski، نويسنده , , Leszek Siergiejczyk، نويسنده , , Piotr Wa?ejko، نويسنده , , Stanis?aw Witkowski، نويسنده , , Stefan Jan Kowalski، نويسنده , , Jolanta P?oszy?ska، نويسنده , , Andrzej Sobkowiak، نويسنده , , Jacek W. Morzycki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
10
From page
8904
To page
8913
Abstract
A new protocol for the electrochemical synthesis of glycoconjugates is presented. Thioether derivatives of cholesterol and other sterols were subjected to anodic oxidation in the presence of a sugar alcohol affording glycoconjugates with the sugar linked to a steroid moiety by an ether bond. The isomeric 6β-3α,5α-cyclo-steroidal thioethers proved to be better sterol donors than the normal 3β-Δ5-steroidal thioethers.
Keywords
Glycosylation , cholesterol , Thioethers , Electrochemical oxidation , Glycoconjugates
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106333
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