Title of article
Highly Diastereoselective Desymmetrisation of Cyclic meso-Anhydrides and Derivatisation to Mono-Protected 1,4-Diols
Author/Authors
Matsuoka، Masato نويسنده , , Ley، Steven V. نويسنده , , Evans، Amanda C. نويسنده , , Longbottom، Deborah A. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-645
From page
646
To page
0
Abstract
A new and efficient desymmetrisation of bi- and tricyclic meso-anhydrides is described, providing good yields and diastereoselectivities in all cases (routinely >95% de). Derivatisation of the chiral compounds synthesised is then demonstrated by their conversion into mono-protected 1,4-diols.
Keywords
anhydride , chiral auxiliary , diastereoselectivity , desymmetrisation , Stereoselective synthesis
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110635
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