• Title of article

    Cu(I)-mediated lactone formation in subcritical water: a benign synthesis of benzopyranones and urolithins A–C

  • Author/Authors

    Prattya Nealmongkol، نويسنده , , Kassrin Tangdenpaisal، نويسنده , , Somkid Sitthimonchai، نويسنده , , Somsak Ruchirawat، نويسنده , , Nopporn Thasana، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    7
  • From page
    9277
  • To page
    9283
  • Abstract
    Benzopyranones were successfully synthesized using Cu(I)-mediated C–O bond formation in subcritical water. A number of benzopyranone derivatives including polymethoxy benzopyranones, benzopyranopyridones, chromenoindolones, and furochromenones were synthesized in satisfactory yield. This methodology was further applied to synthesize the intestinal microbial metabolites, urolithins A, B, and C, which were found to exhibit potent antioxidant activity.
  • Keywords
    benzopyranone , Subcritical water , copper , Microwave , Urolithins
  • Journal title
    Tetrahedron
  • Serial Year
    2013
  • Journal title
    Tetrahedron
  • Record number

    1106380