Title of article
Facile, efficient and diastereoselective synthesis of α-hydrazine tetrazoles through a novel one-pot four-component reaction
Author/Authors
Sorour Ramezanpour، نويسنده , , Saeed Balalaie، نويسنده , , Frank Rominger، نويسنده , , Nahid S. Alavijeh، نويسنده , , Hamid Reza Bijanzadeh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
6
From page
10718
To page
10723
Abstract
A novel and efficient method for the diastereoselective synthesis of α-hydrazine tetrazoles via an isocyanide-based multicomponent reaction is reported in good yields. The α-hydrazine tetrazoles were obtained by a facile azide Ugi four-component reaction (U-4CR) using cyclic ketones, trimethylsilyl azide, hydrazides, and corresponding isocyanide without any catalyst and with high bond forming efficiency at room temperature.
Keywords
?-hyrazino tetrazoles , ?-hyrazino acids , Isocyanide-based multicomponent reaction , Azide Ugi reaction , One-pot four-component reaction
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106553
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