Title of article
A facile asymmetric synthesis of Δ3-2-Hydroxybakuchiol, Bakuchiol and ent-Bakuchiol
Author/Authors
Qian-Qian Xu، نويسنده , , Qun Zhao، نويسنده , , Guang-Sheng Shan، نويسنده , , Xi-Cheng Yang، نويسنده , , Qi-Yuan Shi، نويسنده , , Xinsheng Lei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
8
From page
10739
To page
10746
Abstract
A facile asymmetric synthesis of Δ3-2-Hydroxybakuchiol, Bakuchiol, and ent-Bakuchiol is described through one common intermediate bearing a chiral all-carbon quaternary carbon center, which involves stereoselectively unconjugated alkylation of the α,β-unsaturated imide bearing Evansʹ auxiliary, Takai–Utimoto reaction, Negishi reaction, and Heck reaction as key steps.
Keywords
Stereoselective synthesis , Cross-coupling , Natural products , Chiral quaternary carbon , Unconjugated alkylation
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106556
Link To Document