Title of article :
Tetramethylguanidine as an Inexpensive and Efficient Ligand for the Palladium-Catalyzed Heck Reaction
Author/Authors :
Li، Shenghai نويسنده , , Xie، Haibo نويسنده , , Zhang، Suobo نويسنده , , Lin، Yingjie نويسنده , , Xu، Jianing نويسنده , , Cao، Jungang نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
An inexpensive and efficient Pd(OAc)2/tetramethylguanidine (TMG) or PdCl2/TMG catalytic system has been developed for the Heck reaction of an olefin with an aryl halide. The TONs were up to 1000000 when iodobenzene was used as the substrate with butyl acrylate as the reactant. In addition, [Pd(TMG)4]Cl2(H2O)8, an air-stable compound, effectively promoted the Heck reaction, which demonstrated that TMG acted as a ligand in this reaction system.
Keywords :
tetramethylguanidine , Heck reaction , Palladium , ligand , aryl halides
