Title of article
Indole-benzodiazepine-2,5-dione derivatives from a soil fungus Aspergillus sp. PSU-RSPG185
Author/Authors
Vatcharin Rukachaisirikul، نويسنده , , Nachamon Rungsaiwattana، نويسنده , , Saranyoo Klaiklay، نويسنده , , Chaveng Pakawatchai، نويسنده , , Saowanit Saithong، نويسنده , , Souwalak Phongpaichit، نويسنده , , Kawitsara Borwornwiriyapan، نويسنده , , Jariya Sakayaroj، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
6
From page
11116
To page
11121
Abstract
Six new indole-benzodiazepine-2,5-dione derivatives, asperdiazapinones A–F (1–6), together with three known prenylated indole alkaloids were isolated from the mycelial extract of the soil fungus Aspergillus sp. PSU-RSPG185. Their structures were established by spectroscopic evidence. For compounds 2 and 5, the structures were confirmed by single-crystal X-ray diffraction crystallography. Asperdiazapine B (2) displayed weak antimalarial and noncytotoxic activities.
Keywords
Indole-benzodiazepine-2 , 5-dione , X-ray diffraction crystallography , Cytotoxic activity , Aspergillus sp. , antimalarial activity
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106598
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