Title of article :
Synthesis of 2,3-Dialkylindoles from 2-Alkenylphenylisocyanides and Imines by Silyltelluride- and Tin HydrideMediated Sequential Radical Reactions
Author/Authors :
Yamago، Shigeru نويسنده , , Fukuyama، Tohru نويسنده , , Tokuyama، Hidetoshi نويسنده , , Kotani، Masashi نويسنده , , Satoh، Ayumu نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A new method for the synthesis of 2,3-dialkylindoles is described. The silyltelluride-mediated coupling reaction of imines and 2alkenylphenylisocyanides selectively occurred at the isocyanide moiety to give the corresponding imidoyltelluride. Tin hydridemediated intramolecular cyclization of the imidoyltelluride affords 2,3-dialkylindoles in good to excellent combined yields.
Keywords :
indoles , Cyclization , Tellurium , radical reactions , isocyanides
