Title of article
An efficient synthesis of 4,6-dihydrospiro[azepino[4,3,2-cd]indole-3,3′-indoline]-2′,5(1H)-diones via multi-component reaction
Author/Authors
Bin Zou، نويسنده , , Chun Chen، نويسنده , , Seh Yong Leong، نويسنده , , Mei - Ding Kao، نويسنده , , Paul W. Smith، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
578
To page
582
Abstract
A facile and efficient one-pot three-component synthesis of spiroazepinoindolones has been developed. Using DMF as solvent without any additional acid or metal catalysts, the three-component reaction of readily available isatins, indolamines, and Meldrumʹs acid affords a new class of spiroheterocycles in moderate yield.
Keywords
Spiroazepinoindolone/spirooxindole , Isatin , Meldrumיs acid , multi-component reaction , Indolamine
Journal title
Tetrahedron
Serial Year
2014
Journal title
Tetrahedron
Record number
1106678
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