Author/Authors :
Lee، Jae Hoon نويسنده , , Kim، Young Keun نويسنده , , Choi، Hyeong-wook نويسنده , , Choi، Bo Seung نويسنده , , Chang، Jay Hyok نويسنده , , Lee، Kyu Woong نويسنده , , Nam، Do Hyun نويسنده , , Heo، Taeho نويسنده , , Shin، Hyunik نويسنده , , Kim، No-Soo نويسنده ,
Abstract :
Efficient synthesis of clitocine has been accomplished via unprecedented 1,3-N (endo) to N (exo) migration as a key transformation. Incorporation of p-chlorobenzoyl (PCB) group as a protecting group led to the easy solidification of the intermediate of 7, thus making the isolation very facile and to the minimization of the epimerization of the anomeric center at the final deprotection stage.
Keywords :
1,3-N (endo) to N (exo) migration , Isomerizations , clitocine
