Title of article
Efficient and Stereoselective Synthesis of Precursors for Epoxypolyene Cyclizations via Allylic Substitutions
Author/Authors
Gansauer، Andreas نويسنده , , Justicia، Jose نويسنده , , Rosales، Antonio نويسنده , , Rinker، Bjorn نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-1953
From page
1954
To page
0
Abstract
A catalytic and highly stereoselective approach to precursors for epoxypolyene cyclizations based on copper-catalyzed allylic substitutions is described. The method allows introduction of various aromatic, benzyl, and alkyl groups without affecting epoxides. The compounds obtained are valuable starting materials for the synthesis of natural products and biologically active substances.
Keywords
epoxides , Cuprates , Grignard reagent , epoxypolyene cyclization
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110696
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