Title of article :
Stereofacial Control in Asymmetric Cyanosilylation of Aldehydes Catalyzed by Novel S-Proline-Derived Titanium Complexes
Author/Authors :
Kim، Yong Hae نويسنده , , Kim، Yun Bong نويسنده , , Kim، Min Kyoun نويسنده , , Kang، Sung Ho نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Asymmetric cyanosilylation of aryl aldehydes has been achieved utilizing catalytic amounts of novel chiral ligands. Chiral ligands of amino alcohols and aminophosphine gave S-configured cyanosilylated products with up to 84% ee. In contrast, C2-symmetric ligands resulted in R-configured products with up to 95% ee.
Keywords :
Asymmetric catalysis , cyanohydrin , S-proline derivatives , Stereoselectivity , Lewis acid/base catalysis
