• Title of article

    Conjugation of Selenols with Aziridine-2-Carboxylic Acid-Containing Peptides

  • Author/Authors

    Ide، Nathan D. نويسنده , , Galonic، Danica P. نويسنده , , Donk، Wilfred A. van der نويسنده , , Gin، David Y. نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    -2010
  • From page
    2011
  • To page
    0
  • Abstract
    The addition of PhSeH to aziridine-2-carboxylic acid containing peptides is described, thus expanding the scope of nucleophiles for the opening of this class of electrophilic peptide substrates. The process offers a new strategy for the generation of useful phenylselenocysteine derivatives and (alpha)-seleno-(beta)-amino acid-containing peptides.
  • Keywords
    peptide , aziridine , ligation , selenol , solid-phase
  • Journal title
    Synlett
  • Serial Year
    2005
  • Journal title
    Synlett
  • Record number

    110712