Title of article :
Proline-Catalyzed Asymmetric Direct Aldol Reaction Assisted by DCamphorsulfonic Acid in Aqueous Media
Author/Authors :
Chen، Yi نويسنده , , Cai، Jiwen نويسنده , , Wu، Yin-Su نويسنده , , Deng، Dong-Sheng نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Asymmetric aldol reactions of aromatic aldehydes with various ketones catalyzed by L-proline with D-camphorsulfonic acid as co-catalyst have been developed in aqueous media. High reactivity and modest to excellent enantioselectivity has been achieved.
Keywords :
asymmetric direct aldol reaction , co-catalyst , Proline , camphorsulfonic acid , aqueous media