Title of article
A Straightforward and Convenient Synthesis of Cbz-Protected 2-(1-Aminoalkyl)oxazole-5-carboxylates
Author/Authors
Gatilov، Yuri V. نويسنده , , Trukhin، Dmitry V. نويسنده , , Bagryanskaya، Irina Yu. نويسنده , , Mikhalina، Tatiana V. نويسنده , , Rogozhnikova، Olga Yu. نويسنده , , Troitskaya، Tatiana I. نويسنده , , Tormyshev، Victor M. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2071
From page
2072
To page
0
Abstract
Cbz-protected 2-(1-aminoalkyl)oxazole-5-carboxylates are readily obtainable by a two-step enantioselective sequence involving reaction of benzyloxycarbonyl protected amino acids with (alpha)-chloro-(beta)-ketoesters and subsequent cyclization of the resulting acyloxyketones to required oxazoles upon treatment with neat ammonium trifluoacetate.
Keywords
combinatorial chemistry , aminoalkyloxazolecarboxylates , peptide mimetics
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110740
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