Title of article
Silica Sulfuric Acid Catalyzed One-Pot Synthesis of (alpha)-Aminonitriles
Author/Authors
Lu، Jun نويسنده , , Chen، Wei-Yi نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2292
From page
2293
To page
0
Abstract
A simple and efficient method has been developed for the synthesis of (alpha)aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of silica sulfuric acid at room temperature. The silica sulfuric acid is reusable and could be applied in subsequent reactions with comparable activity.
Keywords
Amine , aldehyde , (alpha)-aminonitrile , silica sulfuric acid , one-pot synthesis
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110743
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