Title of article
Enantioselective Synthesis of Aliphatic Cyanohydrin Acetates
Author/Authors
Veum، Lars نويسنده , , Hanefeld، Ulf نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2381
From page
2382
To page
0
Abstract
When the standard conditions for the enantioselective synthesis of cyanohydrin acetates via dynamic kinetic resolution are applied to aliphatic substrates, only a kinetic resolution is observed. However, by exchanging the base (Amberlite) against NaCN, quantitative conversions and good enantioselectivities are obtained.
Keywords
Candida antarctica lipase B , enzyme catalysis , dynamic kinetic resolution , cyanohydrins , asymmetric synthesis
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110789
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