Title of article :
Trimethylaluminum (TMA)-Catalyzed Reaction of Alkynyllithiums with Ethylene Oxide: Increased Yields and Purity of Homopropargylic Alcohols
Author/Authors :
Brummond، Kay M. نويسنده , , McCabe، Jamie M. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
An efficient protocol was developed to obtain homopropargylic alcohols. Subjecting alkynyllithiums and ethylene oxide to 10-20 mol% of trimethylaluminum provided homopropargylic alcohols in good yields.
Keywords :
alkynyllithiums , Nucleophilic additions , trimethylaluminum , homopropargylic alcohols , ethylene oxide
