Title of article :
Enantioselective Br?nsted Acid Catalyzed Addition Reactions of Methyleneaminopyrrolidine to Imines
Author/Authors :
Dixon، Darren J. نويسنده , , Tillman، A. Louise نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A new series of BINOL-derived multidentate Br?nsted acid catalysts has been developed for the enantioselective addition of the d1-synthon, methyleneaminopyrrolidine, to N-Boc imines, yielding the versatile, protected (alpha)-aminohydrazone intermediates in moderate to good ee.
Keywords :
hydrogen bond donor , hydrazone , asymmetric synthesis , Imines , organocatalysis
