Title of article
A Synthetic Approach to Sporotricale Methylether
Author/Authors
Dallavalle، Sabrina نويسنده , , Nannei، Raffaella نويسنده , , Merlini، Lucio نويسنده , , Bava، Adriana نويسنده , , Nasini، Gianluca نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2675
From page
2676
To page
0
Abstract
A synthetic approach to sporotricale methylether, a metabolite of the fungus Sporotrichum laxum with inhibitory activity against Helicobacter pylori, is described. The synthesis relies on the condensation of 13-hydroxy-10-oxotetradecanal, prepared via reaction of a sulfone-activated moiety with valerolactone, with diethyl 3,5-dimethoxyphthalide-7-phosphonate.
Keywords
total synthesis , sulfones , hydrogenation , condensation , natural products
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110899
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