Title of article :
Preparation of the Neolignan Natural Product Grossamide by a Continuous-Flow Process
Author/Authors :
Ley، Steven V. نويسنده , , Baxendale، Ian R. نويسنده , , Griffiths-Jones، Charlotte M. نويسنده , , Tranmer، Geoffrey K. نويسنده ,
Abstract :
This article describes the first enantioselective total synthesis of 2-aryl-2,3-dihydro-3-benzofurancarboxyamide neolignan, grossamide (1) using a fully automated and scalable flow reactor.
Keywords :
flow synthesis , enzymes , natural products , polymer-supported reagents
Journal title :
Astroparticle Physics
