Title of article :
Conversion of Nucleophilic Halides to Electrophilic Halides: Efficient and Selective Halogenation of Azinones, Amides, and Carbonyl Compounds Using Metal Halide/Lead Tetraacetate
Author/Authors :
Kim، Jeum-Jong نويسنده , , Kweon، Deok-Heon نويسنده , , Cho، Su-Dong نويسنده , , Kim، Ho-Kyun نويسنده , , Lee، Sang-Gyeong نويسنده , , Yoon، Yong-Jin نويسنده ,
Abstract :
AlCl3/Pb(OAc)4 and ZnBr2/Pb(OAc)4 are efficient electrophilic N- and (alpha)-C-halogenating agents. A variety of azinones, amides and carbonyl compounds were chemoselectively and regioselectively N-, or (alpha)-C-halogenated in good to excellent yield using AlCl3/Pb(OAc)4 and ZnBr2/Pb(OAc)4 in acetonitrile.
Keywords :
(alpha)-C-halogenation , selective halogenation , metal halide/lead tetraacetate , N-halogenation , electrophilic halogenation
Journal title :
Astroparticle Physics
