Title of article :
Synthesis of (beta)-Amino Esters by Bismuth Triflate Catalyzed Three-Component Mannich-Type Reaction
Author/Authors :
Ollevier، Thierry نويسنده , , Nadeau، Etienne نويسنده ,
Abstract :
We have developed an efficient, bismuth-catalyzed, Mannich-type three-component reaction by combining the corresponding aldehyde, amine, and silyl ketene acetal. The reaction proceeds rapidly and affords the corresponding (beta)-amino esters in high yields (up to 90%).
Keywords :
Bismuth , multicomponent reactions (MCR) , silyl enolates , amino esters , Green chemistry , Mannich-type reaction
Journal title :
Astroparticle Physics
