• Title of article

    Synthesis of Pyranonaphthoquinone Antibiotics Involving the Phthalide Annulation Strategy

  • Author/Authors

    Kimpe، Norbert De نويسنده , , Claessens، Sven نويسنده , , Naidoo، Dashnie نويسنده , , Mulholland، Dulcie نويسنده , , Verschaeve، Luc نويسنده , , Staden، Johannes van نويسنده ,

  • Pages
    -620
  • From page
    621
  • To page
    0
  • Abstract
    The synthesis of the pyranonaphthoquinone antibiotic pentalongin was performed using the phthalide annulation strategy. Annulation of the cyanophthalide onto 6Hpyran-3-one resulted in a hongconin analogue, which upon further elaboration was converted into the natural product.
  • Keywords
    phthalide , pentalongin , Quinones , annulations , natural products
  • Journal title
    Astroparticle Physics
  • Record number

    111012