• Title of article

    Synthesis of Carbocyclic Pyrimidine Nucleosides Using the Mitsunobu ­Reaction - Part II: Influence of the Solvent on N1versus O^2-Alkylation

  • Author/Authors

    Ludek، Olaf R. نويسنده , , Meier، Chris نويسنده ,

  • Pages
    -323
  • From page
    324
  • To page
    0
  • Abstract
    The influence of the solvent on N- vs O-alkylation of N3-benzoylthymine under Mitsunobu conditions is described. The Mitsunobu reaction is an important tool in carbocyclic nucleoside chemistry for the direct coupling of alcohols with heterocyclic bases under mild conditions.
  • Keywords
    antiviral agents , medicinal chemistry , carbocyclic nucleosides , regio­selectivity , Mitsunobu reaction
  • Journal title
    Astroparticle Physics
  • Record number

    111055

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=111055