Title of article :
Stereoselective Synthesis of an Immunomodulator (+)-Conagenin Using Dirhodium(II)-Catalyzed C-H Amination and Chelation-Controlled Reductions as Key Steps
Author/Authors :
Yakura، Takayuki نويسنده , , Yoshimoto، Yuya نويسنده , , Ishida، Chisaki نويسنده , , Mabuchi، Shunsuke نويسنده ,
Abstract :
Stereoselective synthesis of an immunomodulator (+)-conagenin from commercially available optically active methyl 3-hydroxy-2-methylpropanoate was achieved using dirhodium(II)-catalyzed C-H amination and chelation-controlled reductions as key steps.
Keywords :
immunomodulator , conagenin , dirhodium(II) , C-H amination , chelation control , reduction
Journal title :
Astroparticle Physics
