Title of article :
Metallation versus Heteroatom Lithium Complexation: Mono- and Dilithiation of Dipyridylpiperazines
Author/Authors :
Louerat، Frederic نويسنده , , Gros، Philippe C. نويسنده , , Fort، Yves نويسنده ,
Abstract :
BuLi-LiDMAE induced the efficient lithiation of dipyridylpiperazines despite strong competing lithium coordination by several nitrogen atoms. Symmetrical substrates led to a one-pot dilithiation while dissymmetrical species gave mono- or dilithiation under temperature control.
Keywords :
Heterocycles , pyridine , regioselectivity , Aggregation , Lithiation
Journal title :
Astroparticle Physics
