Title of article
Metallation versus Heteroatom Lithium Complexation: Mono- and Dilithiation of Dipyridylpiperazines
Author/Authors
Louerat، Frederic نويسنده , , Gros، Philippe C. نويسنده , , Fort، Yves نويسنده ,
Pages
-1378
From page
1379
To page
0
Abstract
BuLi-LiDMAE induced the efficient lithiation of dipyridylpiperazines despite strong competing lithium coordination by several nitrogen atoms. Symmetrical substrates led to a one-pot dilithiation while dissymmetrical species gave mono- or dilithiation under temperature control.
Keywords
Heterocycles , pyridine , regioselectivity , Aggregation , Lithiation
Journal title
Astroparticle Physics
Record number
111153
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