Title of article :
A Convenient Approach to (-)-8-epi-Swainsonine
Author/Authors :
Parsons، Philip J. نويسنده , , Murray، Adrian J. نويسنده ,
Abstract :
A novel and efficient synthesis of (-)-8-epi-swainsonine (2) is reported. Face-selective diol formation from the bicyclic alkene 3 followed by a stereoselective vinylation of the aldehyde and ring-closing metathesis gave the indolizidine ring system, which was converted into (-)-8-epi-swainsonine (2).
Keywords :
metathesis , stereoelectronic , indolizidine synthesis , stereoselective
Journal title :
Astroparticle Physics
