Title of article :
A Novel Synthesis of Bicyclo[3.3.0]octane Ring System via a Desymmetric C-H Insertion Reaction
Author/Authors :
Kan، Toshiyuki نويسنده , , Fukuyama، Tohru نويسنده , , Inoue، Tohru نويسنده , , Kawamoto، Yuichiro نويسنده , , Yonehara، Mitsuhiro نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
An optically active bicyclo[3.3.0]octane ring was synthesized by an intramolecular C-H insertion reaction. Upon treatment with a catalytic amount of Rh2(S-DOSP)4, a chiral-auxiliary-containing diazoester underwent a C-H insertion reaction to give the desired bicyclo[3.3.0]octane system.
Keywords :
C-H insertion , piperidinyl mandelamide , chiral auxiliary , Rh2(S-DOSP)4
