Title of article
Protection of radiation-induced protein damage by curcumin Original Research Article
Author/Authors
S. Kapoor and M. S. Sastry، نويسنده , , K.I. Priyadarsini، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
8
From page
119
To page
126
Abstract
Free radical reactions of lysozyme (Lz), tryptophan and disulfides were studied with curcumin, a lipid-soluble antioxidant from turmeric, in aqueous solution using a pulse radiolysis technique. The binding of curcumin with lysozyme was confirmed using absorption, fluorescence and stopped-flow techniques. The free radicals of curcumin generated after repairing radicals of disulfides, lysozyme and tryptophan absorb at 500–510 nm. Implication of this in evaluating the antioxidant behavior of curcumin in protecting proteins is discussed.
Keywords
antioxidant , Electron transfer , Pulse radiolysis , Tryptophan radical , Curcumin , lysozyme
Journal title
Biophysical Chemistry
Serial Year
2001
Journal title
Biophysical Chemistry
Record number
1112983
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