Title of article
The condition for pseudo-first-order kinetics in enzymatic reactions is independent of the initial enzyme concentration Original Research Article
Author/Authors
S. Schnell، نويسنده , , Z. -G. Ji and C. Mendoza، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
10
From page
165
To page
174
Abstract
The linearization of the Michaelis–Menten reaction by pseudo-first-order kinetics is revised. A phase–plane analysis allows the derivation of a new condition for its validity that is directly linked to the reaction efficiency, and contrary to widely established knowledge, is independent of the initial enzyme concentration.
Keywords
Pseudo-first-order kinetics , Michaelis–Menten reaction , Flooding method , Fitting procedure , Progress curves , Rate constants
Journal title
Biophysical Chemistry
Serial Year
2004
Journal title
Biophysical Chemistry
Record number
1113403
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