Title of article :
On the dielectric behaviour of collagen–algal sulfated polysaccharide blends: Effect of glutaraldehyde crosslinking Original Research Article
Author/Authors :
S.D. Figueir?، نويسنده , , A.A.M. Macêdo، نويسنده , , M.R.S. Melo، نويسنده , , A.L.P. Freitas، نويسنده , , R.A. Moreira، نويسنده , , R.S. de Oliveira، نويسنده , , J.C. G?es، نويسنده , , A.S.B. Sombra، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
In this paper, impedance measurements in the frequency range from 10− 2 to 106 Hz are presented for collagen and algal sulfated polysaccharide crosslinked films. We are considering the development of new biomaterials which have potential applications in coating of cardiovascular prostheses, support for cellular growth and in systems for controlled drug delivery. The effect of crosslink sulfated polysaccharide on the physical chemical properties of collagen was studied using FT-infrared spectroscopy, differential scanning calorimetry (DSC), dielectric spectroscopy. The resulting films crosslinked with glutaraldehyde (GA) in concentrations of 0.001% and 0.05% when analysed by DSC, showed that the GA treatment not only left the thermal stability of the collagen unaffected, but it also decreased the thermal transition energy. Dielectric spectroscopy shows that the effect of the crosslink on the blend film was associated to the decrease and stabilization of the dielectric permittivity at low frequencies and decreased its conductivity.
Keywords :
collagen , Sulfated polyssacharide , Glutaraldehyde , Dielectric property
Journal title :
Biophysical Chemistry
Journal title :
Biophysical Chemistry