Serodynamic of Chlamydia Trachomatis Infection in Women with in Vitro Fertilization-Embryo Transfer Failures

The role of Chlamydia trachomatisas one of the main causes of salpinigitis and infertility in women has been well acknowledged. A total of 93 sera was screened with antibodies (IgG) to Chlamydia trachomatisdetected in 31(33.3%) suggesting past infections. All sera tested negative for IgM. Antibodies were found significantly more in patients with tubal damage 12(40.0%) while the least antibodies was found in women with Polycystic ovary syndrome 2(30.0%). Antibodies to Chlamydia trachomatiswere detected 14(45.1%) of the 31 pregnant women and in 26(41.9%) in the 62 of the nonpregnant women. 47women had four embryos transferred and 20 became pregnant with 7(10.0%) of these pregnant having antibodies to Chlamydia trachomatis, while 13(65.0%) were seropositive for C. trachomatis but not pregnant. A total of 214 oocytes was recovered with 199(92.9%) satisfactorily fertilized. There was no difference in fertilization rate of oocytes in-vitro between those with and those withoutantibody to C. trachomatis and between those who became pregnant and those whodid not. Thus, past infected with C. trachomatishalved the success rate of in-vitro fertilization;in these patients. The implications of these findings are relevant to all aspects of infertility particularlyin in-vitro fertilization treatment/procedures.