Abstract :
Benorilate was determined by the differential pulse voltammetry (DPV) using a carbon paste electrode modified by silver nanoparticles in 1.25 × 10^-3 mol l-1 KH2PO4 and Na2HPO4 buffer solution (pH = 6.88, 25 °C) .The anodic peak potential was +0.970 V (versus SCE). A good linear relationship was realized between the anodic peak currents and benorilate concentrations in the range of 1.0 × 10^-7 to 2.5 × 10^-4 mol l-1 with the detection limit of 1.0 × 10^-8 mol l-1. The recovery was 95.2-103.6% with the relative standard deviation of 3.6% (n = 9). The pharmaceutical preparations, benorilate tablets samples and its metabolite (salicylic acid) in urine were determined with the desirable results.
