Title of article
Insertion of a magnesium(II)-octacarboranyl(hexylsulfanyl) porphyrazine into liposomes: A physico-chemical study Original Research Article
Author/Authors
Anna Salvati، نويسنده , , Sandra Ristori، نويسنده , , Daniela Pietrangeli، نويسنده , , Julian Oberdisse، نويسنده , , Luca Calamai، نويسنده , , Giacomo Martini، نويسنده , , Giampaolo Ricciardi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
9
From page
43
To page
51
Abstract
The synthesis, characterization and liposome insertion of a novel magnesium(II) carboranyl-porphyrazine, i.e. [2,3,7,8,12,13,17,18-octakis-(1,2-dicarba-closo-dodecaboranyl)-hexylthio-5,10,15,20-porphyrazine]magnesium(II) complex, MgHECSPz, are described. MgHECSPz was designed to improve the potentiality in multiple approach anticancer therapy. Liposomal formulations with different surface charge were prepared as delivering agents. The obtained loaded vectors were characterized by DLS, SAXS, SANS and zeta potential measurements in order to define the overall properties and structural details of loaded liposomes.
Keywords
Carboranyl-porphyrazines , Drug delivery , liposomes , Zeta potential , SAXS and SANS
Journal title
Biophysical Chemistry
Serial Year
2007
Journal title
Biophysical Chemistry
Record number
1119965
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