Author/Authors :
Runtang Wang، نويسنده , , Paul Cherukuri، نويسنده , , Juan G. Duque، نويسنده , , Tonya K. Leeuw، نويسنده , , Melinda K. Lackey، نويسنده , , Christine H. Moran، نويسنده , , Valerie C. Moore، نويسنده , , Jodie L. Conyers، نويسنده , , Richard E. Smalley، نويسنده , , Howard K. Schmidt، نويسنده , , R. Bruce Weisman، نويسنده , , Paul S. Engel، نويسنده ,
Abstract :
Pristine, individualized single-walled carbon nanotubes (SWCNTs) have been noncovalently captured within PEG-terminated block copolymer amphiphiles. Two cross-linkable amphiphiles were evaluated: polyethylene glycol-polyacrylic acid-polystyrene (PEG-PAA-PS) and polyethylene glycol-polybutadiene (PEG-PB). The resulting self-assembled PEG-PAA-PS structures, called PEG-eggs, are freely soluble in water and stable in physiological media. SWCNTs in PEG-eggs retain their intrinsic near-infrared fluorescence, resist exchange with serum proteins, and are non-cytotoxic to mouse macrophage and human renal cells based on in vitro viability assays.